As companies begin their Digital Transformation journey, they quickly realize that much of Industry 4.0, IIoT and the ability to improve their businesses will depend on the availability of real-time, operational data. This operational data will be one of the main sources on which Advanced Analytics, Artificial Intelligence and Machine Learning techniques will depend in order to provide improved operational decisions. Some companies have already seen benefits from this approach and examples from the Energy, Mining & Metals and Oil & Gas industries will be presented.